About
Hi! I am Lei Hu (胡磊), the second year Ph.D. student of Cell Biology Lab (细胞生物学实验室) at School of Life Sciences, Westlake University, advised by chair professor Hongtao Yu. I am also the Ph.D. student of Artificial Intelligence and Computational Biology (AICB) Lab (人工智能与计算生物学实验室) at the Department of Artificial Intelligence, School of Engineering, co-advised by professor Jianyang Zeng.
My main research interest focus on AI for Life Sciences, supported by the Fundamental Research Project for Young Ph.D. Students from NSFC (国家自然科学基金青年学生基础研究项目(博士研究生)).
💬 Recent News
- December, 2024. I am honored to be supported by the Fundamental Research Project for Young Ph.D. Students from NSFC (国家自然科学基金青年学生基础研究项目(博士研究生)).
- October, 2024. I am honored to receive the National Scholarship !
- September, 2024. Congratulations! My collaborator, Peng Liu has been admitted to Department of Automation, Tsinghua University !
- Jun, 2024. OmicVerse: A Framework for Bridging and Deepening Insights Across Bulk and Single-Cell Sequencing accepted to Nature Communications !
📝 Recent Publications
 | OmicVerse: A Framework for Bridging and Deepening Insights Across Bulk and Single-Cell Sequencing. Zehua Zeng*, Yuqing Ma*, Lei Hu*, Bowen Tan, Peng Liu, Yixuan Wang, Cencan Xing, Yuanyan Xiong, Hongwu Du. Nature Communications, 15, 5983 (2024).  Paper, Biorxiv Code, Reproducibility, Tutorials |
📝 Preprints
[1] Lei Hu*, Peng Liu*, Zheming Zhang*, Yihan Zhao*, Yanchun Wang, Xin Zhang, Shuli Sang, Xiaopeng Cao, Sheng Yao, Yang Fei, Feide Liu, Chunjie Liu, Zehua Zeng, Hongwu Du, ScRNA-seq and Spatial Transcriptome of Gastric Mucosa Discovers the Immune Suppressive Mechanisms in Helicobacter Pylori Infection. (iMetaOmics, under review)
[2] Yihan Zhao*, Peng Liu*, Lei Hu*, Mingxi Ke, Nan Min, Zehua Zeng, Hongwu Du, Chromatin and Gene Regulatory Dynamics of Optic Nerve Invasion in Retinoblastoma at Single-Cell Resolution, bioRxiv, 2023: 2023.05. 10.540147. [BioRxiv]
[3] Zehua Zeng*, Cencang Xing*, Lei Hu*, Shah Roshan, Yuanyan Xiong, Hongwu Du, Identify the origin and end cells and infer the trajectory of cellular fate automatically, bioRxiv, 2022: 2022.09. 28.510020. [BioRxiv]
[4] Yushuai Wu, Ting Zhang, Hao Zhou, Hainan Wu, Hanwen Sunchu, Lei Hu, Xiaofang Chen, Suyuan Zhao, Gaochao Liu, Chao Sun, Jiahuan Zhang, Yizhen Luo, Peng Liu, Zaiqing Nie, Yushuai Wu, DeepCRE: Transforming Drug R&D via AI-Driven Cross-drug Response Evaluation, arXiv preprint arXiv:2403.03768, 2024. [arXiv]
📖 Education
Westlake University
Ph.D. student in Biology, School of Life Sciences, advised by Prof. Hongtao Yu and Prof. Jianyang Zeng. 2023.08 - Present
University of Science and Technology Beijing （GPA: 3.76/4.0）
B.E. in Automation, School of Advanced Engineering, advised by Prof. Hongwu Du at 112lab and Lecturer Rongbin Li. 2019.09-2023.06
University of Science and Technology Beijing
B.S. in Biotechnology, School of Chem. and Bio. Engineering. 2020.09-2023.06
Central South University （GPA: 4.0/4.0）
Exchange Student, School of Automation, 2021.09-2022.01
👑 Awards and Honors
- 2024: Fundamental Research Project for Young Ph.D. Students from NSFC (国家自然科学基金青年学生基础研究项目(博士研究生))
- 2024: National Scholarship
- 2024: Innovation Awards, Westlake University
- 2023: Dean Award (Top Award of Undergraduate Students)
- 2023: “San Hao” Graduate
- 2023: Outstanding Graduation Thesis of USTB
- 2022: Zhongtian Steel Scholarship
- 2022: Huawei Intelligent Base Scholarship
- 2021: Tongda Scholarship (1/146)
- 2021: Outstanding “San Hao” Student
- 2020: People Scholarship (First Class)
🎤 Talks
- New functions and progress of OmicVerse, the python based framework for transcriptome data analysis, BiolinkX, Zhejiang University, September 2024.
- OmicVerse - Introduction to the python based framework for transcriptome data analysis, BiolinkX, Online, September 2023.
💻 Internships
- 2023.03 - 2023.07 Research Intern at AIR, Tsinghua University, advised by Prof. Zaiqing Nie and Postdoc Yushuai Wu.
- 2021.11 - 2023.08 Research Intern at 112Lab, University of Science and Techonology Beijing, advised by Prof. Hongwu Du and Ph.D. Student Zehua Zeng .
- 2021.07 - 2022.07 Research Intern at APM, Chinese Academy of Science, advised by Prof. Fuchun Lin.
- 2020.09 - 2021.09 Research Intern at Metall, University of Science and Techonology Beijing, advised by Lecturer Rongbin Li.
🔗 Co-working Students
(I am working with some visiting/undergraduate/doctoral students and postdocs at Westlake University with chair professor Hongtao Yu and professor Jianyang Zeng)
- Peng Liu (undergraduate student at USTB → THU)
- Yihan Zhao (undergraduate student at USTB → FDU)
- Zheming Zhang (undergraduate student at CSU)
- Fenglei Zhang (undergraduate student at SXU → NPU)
- Zhaorui Jiang (undergraduate student at OUC → PKU)
- Haoteng Gu (undergraduate student at BJUT)
- Peiran Ling (undergraduate student at SDU → Westlake)